Bert K.B.Lum: search on Z-Library

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1

The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP™) predicts in vivo metabolic inhibition

Ashok Rakhit, Michael P. Pantze, Scott Fettner, Hannah M. Jones, Jean-Eric Charoin, Myriam Riek, Bert L. Lum, Marta Hamilton

Journal:

European Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 260 KB

english, 2008

2

Subcutaneous versus intravenous administration of (neo)adjuvant trastuzumab in patients with HER2-positive, clinical stage I–III breast cancer (HannaH study): a phase 3, open-label, multicentre, randomised trial

Gustavo Ismael, Roberto Hegg, Susanne Muehlbauer, Dominik Heinzmann, Bert Lum, Sung-Bae Kim, Tadeusz Pienkowski, Mikhail Lichinitser, Vladimir Semiglazov, Bohuslav Melichar, Christian Jackisch

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 245 KB

english, 2012

3

Single and multiple dose intravenous and oral pharmacokinetics of the hedgehog pathway inhibitor vismodegib in healthy female subjects

Graham, Richard A., Hop, Cornelis E. C. A., Borin, Marie T., Lum, Bert L., Colburn, Dawn, Chang, Ilsung, Shin, Young G., Malhi, Vikram, Low, Jennifer A., Dresser, Mark J.

Journal:

British Journal of Clinical Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

4

Tamoxifen in advanced prostatic carcinoma. A dose escalation study

Frank M. Torti, Bert L. Lum, Richard Lo, Fuad Freiha, Linda Shortliffe

Journal:

Year:

1984

Language:

english

File:

PDF, 431 KB

english, 1984

5

A randomized study of doxorubicin versus doxorubicin plus cisplatin in endocrine-unresponsive metastatic prostatic carcinoma

Frank M. Torti, Linda D. Shortliffe, Stephen K. Carter, John F. Hannigan JR, Diana Aston, Vmd, Bert L. Lum, Richard D. Williams, Joseph T. Spaulding, Fuad S. Freiha

Journal:

Year:

1985

Language:

english

File:

PDF, 619 KB

english, 1985

6

Superficial bladder cancer. Risk of recurrence and potential role for interferon therapy

Frank M. Torti, Bert L. Lum Pharmd

Journal:

Year:

1987

Language:

english

File:

PDF, 479 KB

english, 1987

7

The use of probenecid as a chemoprotector against cisplatin nephrotoxicity

Charlotte Jacobs, Sonja Kaubisch, Joanne Halsey, Bert L. Lum, Michael Gosland, C. Norman Coleman, Branimir I. Sikic

Journal:

Year:

1991

Language:

english

File:

PDF, 669 KB

english, 1991

8

Clinical trials of modulation of multidrug resistance pharmacokinetic and pharmacodynamic considerations

Bert L. Lum, George A. Fisher, Nathalie A. Brophy, Anne M. Yahanda, Kent M. Adler, Sonja Kaubisch, Joanne Halsey, Branimir I. Sikic

Journal:

Year:

1993

Language:

english

File:

PDF, 1.27 MB

english, 1993

9

A Phase II trial of aprinocarsen, an antisense oligonucleotide inhibitor of protein kinase C α, administered as a 21-day infusion to patients with advanced ovarian carcinoma

Ranjana Advani, Prema Peethambaram, Bert L. Lum, George A. Fisher, Lynn Hartmann, Harry J. Long, Joanne Halsey, Jon T. Holmlund, Andrew Dorr, Branimir I. Sikic

Journal:

Year:

2004

Language:

english

File:

PDF, 77 KB

english, 2004

10

Effects of the PAF antagonists bepafant and L-659, 989 in endotoxic and septic shock

Hai Ming Tang, Dick Y. Teshima, Bert K. B. Lum

Journal:

Drug Development Research

Year:

1993

Language:

english

File:

PDF, 550 KB

english, 1993

11

Quantitative structure–pharmacokinetic parameters relationships (QSPKR) analysis of antimicrobial agents in humans using simulated annealing k-nearest-neighbor and partial least-square analysis methods

Chee Ng, Yunde Xiao, Wendy Putnam, Bert Lum, Alexander Tropsha

Journal:

Journal of Pharmaceutical Sciences

Year:

2004

Language:

english

File:

PDF, 125 KB

english, 2004

12

Long-term results of irradiation for patients with progressive GRAVES’ ophthalmopathy

Sheri D Marquez, Bert L Lum, I.Ross McDougall, Shobha Katkuri, Peter S Levin, Michael MacManus, Sarah S Donaldson

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 112 KB

english, 2001

13

Rapid determination of PEGylated liposomal doxorubicin and its major metabolite in human plasma by ultraviolet–visible high-performance liquid chromatography

David L Chin, Bert L Lum, Branimir I Sikic

Journal:

Journal of Chromatography B

Year:

2002

Language:

english

File:

PDF, 449 KB

english, 2002

14

Phase I study of valspodar (PSC-833) with mitoxantrone and etoposide in refractory and relapsed pediatric acute leukemia: A report from the Children's Oncology Group

Maureen M. O'Brien, Norman J. Lacayo, Bert L. Lum, Smita Kshirsagar, Steven Buck, Yaddanapudi Ravindranath, Mark Bernstein, Howard Weinstein, Myron N. Chang, Robert J. Arceci, Branimir I. Sikic, Gary

Journal:

Pediatric Blood & Cancer

Year:

2010

Language:

english

File:

PDF, 179 KB

english, 2010

15

Preliminary observations of intraperitoneal carboplatin pharmacokinetics during a phase I study of the Northern California Oncology Group

Michael W. DeGregorio, Bert L. Lum, Walter M. Holleran, Bruce J. Wilbur, Branimir I. Sikic

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1986

Language:

english

File:

PDF, 403 KB

english, 1986

16

Effect of different mathematical methods on etoposide area under the curve estimations and pharmacodynamic response predictions

Dayna L. McCauley, Bert L. Lum, Branimir I. Sikic

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1996

Language:

english

File:

PDF, 299 KB

english, 1996

17

Pharmacokinetics and safety of bevacizumab administered in combination with cisplatin and paclitaxel in cynomolgus monkeys

Lu Xu, Christina L. Zuch, Yvonne S. Lin, Nishit B. Modi, Bert L. Lum

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 420 KB

english, 2008

18

Clinical pharmacokinetics of bevacizumab in patients with solid tumors

Jian-Feng Lu, Rene Bruno, Steve Eppler, William Novotny, Bert Lum, Jacques Gaudreault

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2008

Language:

english

File:

PDF, 389 KB

english, 2008

19

Effect of high-dose cyclosporine on etoposide pharmacodynamics in a trial to reverse P-glycoprotein (MDR1gene) mediated drug resistance

Bert L. Lum, Sonja Kaubisch, George A. Fisher, Byron W. Brown, Branimir I. Sikic

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2000

Language:

english

File:

PDF, 134 KB

english, 2000

20

Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein

B. I. Sikic, George A. Fisher, Bert L. Lum, Joanne Halsey, Lidija Beketic-Oreskovic, Gang Chen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1997

Language:

english

File:

PDF, 158 KB

english, 1997

21

A phase I trial of aprinocarsen (ISIS 3521/LY900003), an antisense inhibitor of protein kinase C-α administered as a 24-hour weekly infusion schedule in patients with advanced cancer

Ranjana Advani, Bert L. Lum, George A. Fisher, Joanne Halsey, Richard S. Geary, Jon T. Holmlund, T. Jesse Kwoh, F. Andrew Dorr, Branimir I. Sikic

Journal:

Investigational New Drugs

Year:

2005

Language:

english

File:

PDF, 123 KB

english, 2005

22

Pharmacokinetic study of the phase III, randomized, double-blind, multicenter trial (TRIBUTE) of paclitaxel and carboplatin combined with erlotinib or placebo in patients with advanced Non-small Cell Lung Cancer (NSCLC)

Hai T. Tran, Ralph G. Zinner, George R. Blumenschein, Yun W. Oh, Vassiliki A. Papadimitrakopoulou, Edward S. Kim, Charles Lu, Mubashira Malik, Bert L. Lum, Roy S. Herbst

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 156 KB

english, 2011

23

Rationale for Fixed Dosing of Pertuzumab in Cancer Patients Based on Population Pharmacokinetic Analysis

Chee M. Ng, Bert L. Lum, Veronica Gimenez, Steve Kelsey, David Allison

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 893 KB

english, 2006

24

Statin-AE: A novel angiostatin–endostatin fusion protein with enhanced antiangiogenic and antitumor activity

Frank A. Scappaticci, Anthony Contreras, Richard Smith, Loic Bonhoure, Bert Lum, Yihai Cao, Edgar G. Engleman, Garry P. Nolan

Journal:

Year:

2001

Language:

english

File:

PDF, 716 KB

english, 2001

25

Insights into Mechanisms of Cisplatin Resistance and Potential for Its Clinical Reversal

Dr. Michael Gosland, Dr. Bert Lum, Dr. Julia Schimmelpfennig, Dr. James Baker, Dr Michael Doukas

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1996

Language:

english

File:

PDF, 2.31 MB

english, 1996

26

Dihydropyrimidine Dehydrogenase Deficiency: A Potential Etiology for 5-Fluorouracil-Induced Neurotoxicity

Marlis E. Risso, Dr. Noelle K. Hasson, Dr. Bert L. Lum

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1997

Language:

english

File:

PDF, 149 KB

english, 1997

27

Validation of a Limited Sampling Model to Determine Etoposide Area Under the Curve

Bert L. Lum, Kevin J. Lane, Timothy W. Synold, Adrian Goram, Steven B. Charnick, Branimir I. Sikic

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1997

Language:

english

File:

PDF, 381 KB

english, 1997

28

Quantitative structure–activity relationships of methotrexate and methotrexate analogues transported by the rat multispecific resistance-associated protein 2 (rMrp2)

Chee Ng, Yun-De Xiao, Bert L. Lum, Yong-Hae Han

Journal:

European Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 225 KB

english, 2005

29

A Graphic Nomogram for Warfarin Dosage Adjustment

Dr. Gloriann M. Dalere, Mr. Robert W. Coleman, Dr. Bert L. Lum

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1999

Language:

english

File:

PDF, 77 KB

english, 1999

30

A Phase I/II Trial of Trastuzumab plus Erlotinib in Metastatic HER2-Positive Breast Cancer: A Dual ErbB Targeted Approach

Carolyn D. Britten, Richard S. Finn, Linda D. Bosserman, Steven G. Wong, Michael F. Press, Mubashira Malik, Bert L. Lum, Dennis J. Slamon

Journal:

Clinical Breast Cancer

Year:

2009

Language:

english

File:

PDF, 119 KB

english, 2009

31

Effects of nicardipine in rats subjected to endotoxic shock

Hing-Chung Lee, John.M. Hardman, Bert.K.B. Lum

Journal:

General Pharmacology: The Vascular System

Year:

1992

Language:

english

File:

PDF, 339 KB

english, 1992

32

Selective loss of responsiveness to alpha adrenergic receptor stimulation after cold storage of the rabbit intestine

Bert K.B. Lum, Richard D. Heilman, Mary A. Gaunt

Journal:

European Journal of Pharmacology

Year:

1967

Language:

english

File:

PDF, 403 KB

english, 1967

33

Cardiovascular interactions of amphetamine and ephedrine with norepinephrine and with vasopressin

Michael A. Commarato, Bert K.B.Lum

Journal:

European Journal of Pharmacology

Year:

1969

Language:

english

File:

PDF, 759 KB

english, 1969

34

Potentiation of the pressor response to angiotensin by amphetamine and ephedrine

Michael A. Commarato, Bert K.B. Lum

Journal:

European Journal of Pharmacology

Year:

1970

Language:

english

File:

PDF, 667 KB

english, 1970

35

The effects of the calcium entry blockers, nilvadipine and nitrendipine, on endotoxin-induced disseminated intravascular coagulation

Hing-Chung Lee, John M. Hardman, Bert K.B. Lum

Journal:

Year:

1989

Language:

english

File:

PDF, 428 KB

english, 1989

36

Selective adrenergic stimulant actions of 1-isopropylamino-3- (2-thiazoloxy)-2-propanol (ITP) in anesthetized cats

Raymond H. Lockwood, Bert K.B. Lum

Journal:

Year:

1974

Language:

english

File:

PDF, 285 KB

english, 1974

37

Studies on the hyperglycemia and hepatic glycogenolysis produced by alpha and beta adrenergic agonists in the cat

Bert K.B. Lum, Yuen-Sum Lau, Reginald Buesa, Raymond H. Lockwood, Shu-Hui Kuo

Journal:

Year:

1980

Language:

english

File:

PDF, 446 KB

english, 1980

38

Phase II trial of the histone deacetylase inhibitor pivaloyloxymethyl butyrate (Pivanex, AN-9) in advanced non-small cell lung cancer

Reid, Tony, Valone, Frank, Lipera, William, Irwin, David, Paroly, Warren, Natale, Ron, Sreedharan, Sunil, Keer, Harold, Lum, Bert, Scappaticci, Frank, Bhatnagar, Anish

Journal:

Year:

2004

Language:

english

File:

PDF, 145 KB

english, 2004

39

Antibody delivery of drugs and radionuclides: factors influencing clinical pharmacology

Prabhu, Saileta, Boswell, C Andrew, Leipold, Douglas, Khawli, Leslie A, Li, Dongwei, Lu, Dan, Theil, Frank-Peter, Joshi, Amita, Lum, Bert L

Journal:

Therapeutic Delivery

Year:

2011

Language:

english

File:

PDF, 2.79 MB

english, 2011

40

Identification, Characterization, and Implications of Species-Dependent Plasma Protein Binding for the Oral Hedgehog Pathway Inhibitor Vismodegib (GDC-0449)

Giannetti, Anthony M., Wong, Harvey, Dijkgraaf, Gerrit J. P., Dueber, Erin C., Ortwine, Daniel F., Bravo, Brandon J., Gould, Stephen E., Plise, Emile G., Lum, Bert L., Malhi, Vikram, Graham, Richard A

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

41

Evaluation of the Absolute Oral Bioavailability and Bioequivalence of Erlotinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in a Randomized, Crossover Study in Healthy Subjects

Frohna, Paul, Lu, Jianfeng, Eppler, Steve, Hamilton, Marta, Wolf, Julie, Rakhit, Ashok, Ling, Jie, Kenkare-Mitra, Saraswati R., Lum, Bert L.

Journal:

Journal of Clinical Pharmacology

Year:

2006

Language:

english

File:

PDF, 197 KB

english, 2006

42

Prevalence of Acid-Reducing Agents (ARA) in Cancer Populations and ARA Drug–Drug Interaction Potential for Molecular Targeted Agents in Clinical Development

Smelick, Gillian S., Heffron, Timothy P., Chu, Laura, Dean, Brian, West, David A., DuVall, Scott L., Lum, Bert L., Budha, Nageshwar, Holden, Scott N., Benet, Leslie Z., Frymoyer, Adam, Dresser, Mark J

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 840 KB

english, 2013

43

The effect of rifampicin, a prototypical CYP3A4 inducer, on erlotinib pharmacokinetics in healthy subjects

Hamilton, Marta, Wolf, Julie L., Drolet, Daniel W., Fettner, Scott H., Rakhit, Ashok K., Witt, Karsten, Lum, Bert L.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 517 KB

english, 2014

44

Population pharmacokinetics and exposure–response analyses of trastuzumab in patients with advanced gastric or gastroesophageal junction cancer

Cosson, Valérie F., Ng, Vivian W., Lehle, Michaela, Lum, Bert L.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

45

Comparative pharmacokinetics of subcutaneous trastuzumab administered via handheld syringe or proprietary single-use injection device in healthy males

Wynne, Chris J., Ellis-Pegler, Rod B., Waaka, Devonie S., Schwabe, Christian, Lehle, Michaela, Heinzmann, Dominik, Mangat, Ranvir, Li, Chunze, Dick, Anne E., Cranshaw, Nicola A., Lum, Bert L.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 499 KB

english, 2013

46

Exposure–response analysis of pertuzumab in HER2-positive metastatic breast cancer: absence of effect on QTc prolongation and other ECG parameters

Garg, Amit, Li, Jing, Clark, Emma, Knott, Adam, Carrothers, Timothy J., Marier, Jean-François, Cortés, Javier, Brewster, Michael, Visich, Jennifer, Lum, Bert

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2013

Language:

english

File:

PDF, 512 KB

english, 2013

47

Experimental Studies on the Effects of Physostigmine and of Isoproterenol on Toxicity Produced by Tricyclic Antidepressant Agents

Lum, Bert K. B., Follmer, Christopher H., Lockwood, Raymond H., Thomas, Harry M.

Journal:

Clinical Toxicology (Informa Healthcare)

Year:

1982

Language:

english

File:

PDF, 701 KB

english, 1982

48

Trastuzumab, in combination with carboplatin and docetaxel, does not prolong the QT interval of patients with HER2-positive metastatic or locally advanced inoperable solid tumors: results from a phase Ib study

Xu, Na, Redfern, Charles H., Gordon, Michael, Eppler, Stephen, Lum, Bert L., Trudeau, Caroline

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 253 KB

english, 2014

49

Lack of a pharmacokinetic interaction between trastuzumab and carboplatin in the presence of docetaxel

Eppler, Stephen, Gordon, Michael S., Redfern, Charles H., Trudeau, Caroline, Xu, Na, Han, Kelong, Lum, Bert L.

Journal:

Anti-Cancer Drugs

Year:

2015

Language:

english

File:

PDF, 181 KB

english, 2015

50

Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer

Calvert, Hilary, Twelves, Chris, Ranson, Malcolm, Plummer, Ruth, Fettner, Scott, Pantze, Michael, Ling, Jie, Hamilton, Marta, Lum, Bert L., Rakhit, Ashok

Journal:

Anti-Cancer Drugs

Year:

2014

Language:

english

File:

PDF, 561 KB

english, 2014

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